Biology

An accidental gunshot wound left Alexis St. Martin with a permanent hole in his chest in 1822. This wound enabled Dr. William Beaumont to study what vital organ?

The Stomach
http://en.wikipedia.org/wiki/William_Beaumont

Geography

Only 3 country names begin with the letters "O" "Q" and "Y" (one nation per letter). What are the names of these countries?

Oman, Qatar, and Yemen
http://en.wikipedia.org/wiki/Oman
http://en.wikipedia.org/wiki/Qatar
http://en.wikipedia.org/wiki/Yemen

Astronomy

In 2015, The Dawn spacecraft will reach Ceres, the largest asteroid in the solar system. Between which planets will you find Ceres?

Between Mars and Jupiter - in the asteroid belt
https://en.wikipedia.org/wiki/Ceres_%28dwarf_planet%29

U.S. History

On August 4, 1922, every phone in North America went silent to honor the passing of what man?

Alexander Graham Bell
http://idiotsguides.com/static/didyouknow/unitedstateshistory/03-10-11-bell-telephone.html

English

What famous British man invented over 1700 of the common English words we use?

William Shakespeare
http://www.shakespeare-online.com/biography/wordsinvented.html

U.S. History

David Atchison served as President of the United States for 1 day. What day of the week was it?

Sunday. He was Vice President to James Polk, whose term ended the day before, but the new president-elect, Zachary Taylor, would not be sworn in on Sunday.
http://idiotsguides.com/static/didyouknow/unitedstateshistory/02-23-11-shortest-term.html

Movies

What Muppet character made a cameo appearance on the blooper reel for Star Wars: The Empire Strikes Back?

Miss Piggy
http://idiotsguides.com/static/didyouknow/artsentertainment/02-16-11-miss-piggy.html

Literature

How many total unique words are there in the children's book "Green Eggs and Ham" by Dr. Seuss?

43
http://idiotsguides.com/static/didyouknow/artsentertainment/08-23-11-seuss.html

World History

What invention served as the catalyst for the creation of time zones in the 1800s?

Trains
http://en.wikipedia.org/wiki/Time_zone

World History

What board game was used during World War II by the British as an escape kit for POWs?

Monopoly
http://abcnews.go.com/Technology/monopolys-hidden-maps-wwii-pows-escape/story?id=8605905#.UYgan8p48Yo

Dates and Times

In September 1752, the British Empire replaced the Julian calendar with the Gregorian calendar. How many days were "lost" due to this transition?

11 days. The Julian calendar counts leap days differently than the Gregorian, so there was a discrepancy.
http://en.wikipedia.org/wiki/Gregorian_calendar

Games

Founded in 1889 and now worth $1 trillion, what company started out making card games long before changing the video game landscape forever?

Nintendo
http://idiotsguides.com/static/didyouknow/popculture/09-26-11-nintendo.html

Musical Instruments

A crwth (yes, there are no vowels) is a 6-string musical instrument, usually played like a violin, but with a neck-strap. Where in Europe did it originate?

Wales
http://en.wikipedia.org/wiki/Crwth

Toys

Created in 1949 and selling 28 boxes worldwide every second, what toy's name comes from the Danish phrase "play well"?

Lego
http://www.deseretnews.com/article/865570837/Why-Legos-are-so-expensive-yet-your-mom-still-got-them-for-your-birthday.html?pg=all http://en.wikipedia.org/wiki/Lego

Geography

What city is the only U.S. capital that has 3 words in its name?

Salt Lake City
http://en.wikipedia.org/wiki/List_of_capitals_in_the_United_States

Flags

What U.S. state flag displays a woman standing with her foot on a dead man?

Virginia

Movies

Halfway between the Dead Sea and the Red Sea, in Jordan, the ancient city of Petra was discovered in 1812. What blockbuster movie's climax supposedly takes place inside Petra's Al Khazneh temple?

Indiana Jones and The Last Crusade
http://en.wikipedia.org/wiki/Petra

Geography

By using the Mississippi River and latitude lines as borders for one U.S. state, it created a peninsula that belongs to that state, but by land is only connected to another state. What state owns this enclave?

Kentucky
http://en.wikipedia.org/wiki/Kentucky_Bend

Flags

What U.S. state has the only flag with 2 different designs on each side?

Oregon

Geography

What are the only 2 countries in the world that are doubly landlocked (meaning they only border landlocked countries)?

Liechtenstein (Borders Switzerland and Austria)
and
Uzbekistan (Borders Afghanistan, Kazakhstan, Kyrgyzstan, Tajikistan, and Turkmenistan)
http://en.wikipedia.org/wiki/Landlocked_country

Physics

What happens when you wring out a washcloth in zero gravity?

The water sticks on the cloth and hands (watch the video below)

Geography

Mount Mitchell, the tallest mountain east of the Mississippi, is located in what US state?

North Carolina
http://en.wikipedia.org/wiki/Mount_Mitchell